Research Funding & Allocation Tracker

Federal program dedicated to asthma prevention, surveillance, and supporting community-based interventions to reduce asthma deaths and hospitalizations.

General food allergy research studies conducted in North America to improve quality of life and health.

Investigates the mechanisms underlying alpha-gal syndrome (AGS), focusing on why some individuals develop clinically evident meat allergy after tick bites while others remain asymptomatic.

Promoting clinical and basic research in diseases including asthma, upper airway allergic/inflammatory diseases, food and drug allergies, and atopic dermatitis.

Focus on new discoveries in basic or translational medical sciences that impact the understanding or treatment of atopic dermatitis.

Planning and implementation grants for food access and food allergy management.

Investigating the Ras signaling pathway as a regulator of Tr1 cell development and maintenance in the context of allergic asthma.

Research network focused on the mechanisms and treatment of atopic dermatitis.

Supporting forefront research in the field of allergy and immunology.

Supports proximal translational research to accelerate breakthroughs in food allergy treatment and management.

Innovative approaches to identifying the causes of food allergies or developing improved treatments.

Supporting faculty in clinical allergy and immunology divisions to advance understanding of allergic respiratory disease.

Advancing personalized treatment strategies for peanut allergy by identifying biomarkers and biological pathways that predict response.

Innovative research focused on understanding and improving the treatment of allergic respiratory diseases.

Proximal translational research using convergence science to accelerate breakthroughs in food allergy treatment.

This center executes clinical trials focused on food allergy prevention and management, including research into the mechanisms underlying alpha-gal syndrome and peanut allergy prevention in at-risk infants.

Accelerating research to find a cure for food allergies.

Promoting innovative, multidisciplinary clinical and basic research on asthma and allergic diseases.

Development of new medical countermeasures for infectious and respiratory threats including Aspergillus fumigatus.

Supports clinical studies and mechanistic investigations into the development and prevention of food allergies as a designated CoFAR Clinical Research Center.

A venture philanthropy fund designed to accelerate innovation in celiac disease treatments and diagnostics.

Studying the effect of complement proteins on mast cells and fibroblasts in Eosinophilic Esophagitis.

A multidisciplinary project investigating novel modes of G protein-coupled receptor (GPCR) regulation to develop more effective asthma drugs and reduce disease disparities.

Advancing FDA-approved treatment options for people with food allergies and increasing support for clinical research.

Clinical research focused on improving the management and outcomes for patients living with Chronic Obstructive Pulmonary Disease.

Investigating neurological and neuropsychological symptoms and brain-related manifestations of celiac disease.

Investigating how T2-skewed basal cells promote small airway mucus plugging in asthma.

Exploring how maternal skin health and environmental exposures during pregnancy influence the risk of eczema in children.

A multi-center randomized trial comparing the effectiveness of FDA-approved biologics (Dupilumab, Omalizumab, and Mepolizumab) for chronic sinusitis with nasal polyps to identify biomarkers that predict treatment response.

A multidisciplinary research program testing the central hypothesis that novel modes of G protein-coupled receptor (GPCR) regulation can be targeted for superior management of airway smooth muscle function and asthma. Led by Raymond B. Penn, PhD, with collaborators at Mayo Clinic, Rutgers University, and Stanford University. Comprises four collaborative projects and 3 cores focused on discovering new asthma drugs.

Supports implementation science and community evaluation of digital self-management and education platforms for underserved asthma populations.

Investigates the role of the MRGPRX2 receptor in mast cell activation and its connection to drug-induced anaphylaxis in patients with mast cell diseases.

Providing bridge funding to sustain research excellence for junior investigators.

Exploring the PM2.5 associated inflammatory endotype of chronic rhinosinusitis.

Tracks a cohort of pregnant women in Queens, New York, working with community partners to explore how prenatal exposure to indoor air pollution affects lung development and future disease risk.

A pilot trial of POIT (Peanut Oral Immunotherapy) in children diagnosed with peanut-induced Food Protein-Induced Enterocolitis Syndrome (FPIES).

Developing innovative immunotherapeutic tools targeting allergens from house dust mites, cats, and dogs — major contributors to allergic reactions and asthma. The project identifies specific IgE epitopes that trigger immune responses and designs hypoallergenic molecules for potential use in immunotherapy. Collaborators include Michigan State University, University of Virginia, and NIEHS.

Investigating the association between gut-homing T cells, gastrointestinal adverse events in peanut oral immunotherapy, and Eosinophilic Esophagitis.

Providing $100,000 annually for three years to mid-career investigators conducting research into Type 2 inflammation in skin.

Supports potential treatment or prevention trials and clinical research for food allergies, including Alpha-gal syndrome, FPIES, and EoE.

Network of researchers focused on understanding the biological mechanisms of food allergies.

Advancing basic immunological and neuro-immune mechanisms underlying food allergy onset and potential therapies.

A randomized trial comparing three FDA-approved biologics to determine relative effectiveness and develop mucus biomarkers to predict patient response.

Advancing food allergy understanding and treatment options through collaborative research across immunology, neuroscience, and computational biology.

Development of better asthma drugs and improved management strategies.

Studies to determine the clinical and cost-effectiveness of step-up treatments for individuals whose asthma is uncontrolled on standard low-dose combination inhalers.

Supporting junior investigators in the field of allergy and immunology to sustain research excellence.

Tests whether tezepelumab, which blocks TSLP, can reduce nasal symptoms and inflammation in patients suffering from both asthma and allergic rhinitis.

Investigates the mechanistic role of monocytes in human asthma flare-ups and airway inflammation with the goal of blocking eosinophil accumulation.

Investigating how mast cells and complement proteins interact with fibroblasts to drive inflammation and scarring in the esophagus.

Investigates whether low levels of the lung protein CC16 in childhood can predict the risk of developing early chronic obstructive pulmonary disease later in life.

Supports developing innovative immunotherapeutic tools targeting allergens from house dust mites, cats, and dogs to advance safer and more effective treatments for allergic asthma.

Improving how children with asthma receive care and management within the school environment.

Supporting mid-career investigators conducting research into Type 2 inflammation in skin conditions like atopic dermatitis.

A randomized trial of 500 patients to compare the effectiveness of different biologic drugs for chronic sinusitis with nasal polyps.

Investigating the underlying mechanisms of food allergy pathogenesis.

Testing whether low levels of the CC16 lung protein in childhood can predict the development of early-onset COPD in adulthood.

Addressing serious respiratory infections and health hazards, including influenza, SARS-CoV-2, and tuberculosis, to bolster national health security and pandemic preparedness.

Building and supporting community-based interventions to address inequities in asthma and allergic diseases.

Unraveling complex immune mechanisms that cause the body to attack its own tissues following gluten exposure.

Research into allergic respiratory diseases.

Investigates the interaction between mast cells and fibroblasts in the esophagus to understand their role in tissue damage and stricture formation in EoE.

Investigating whether childhood levels of the lung protein CC16 can serve as a biomarker to predict the risk of early-onset COPD later in life.

Continued research into the neurological and neuropsychological manifestations of celiac disease and other gluten-related disorders.

This study investigates the role of the MRGPRX2 receptor in mast cell activation and its connection to drug-induced anaphylaxis in patients with mast cell disorders.

Conducting fundamental immunology research and clinical trials for immune-mediated diseases.

Advancing the understanding of allergic respiratory disease to improve care and outcomes for patients.

Investigating the roles of mast cells (allergic immune cells) and their interactions with fibroblasts (structural cells) in eosinophilic esophagitis (EoE), exploring whether interrupting that interaction could prevent inflammation and tissue damage. Conducted through the Cincinnati Center for Eosinophilic Disorders (CCED).

Examines how the Inflation Reduction Act's lower medication costs affect access to inhalers for older adults with asthma and COPD, and assesses whether the policy helps Black and Hispanic adults obtain inhalers to improve their health.

Advocacy, development of educational tools, and research into health equity and access to care for asthma and allergy patients.

Supporting innovative research studies in the field of food allergy.

Determining whether an mRNA vaccine can induce acquired tick resistance against the lone star tick to prevent red meat allergy (alpha-gal syndrome).

Advancing scientific knowledge and treatment options specifically for tree nut allergies.

Investigates the association between activated, gut-homing T cells and gastrointestinal adverse events during peanut oral immunotherapy, specifically focusing on patients who develop EoE.

Exploring the PM2.5 associated inflammatory endotype of chronic rhinosinusitis to understand environmental triggers.

New research grants, clinical research, and strategic partnerships to advance understanding, diagnosis, treatment, and prevention of lung disease. Supports 130 researchers including the Airways Clinical Research Centers (ACRC) Network — the nation's largest nonprofit network of clinical research centers dedicated to asthma and COPD treatment research. Includes Allergic Respiratory Diseases Award, Respiratory Health Equity Research Award, and Indoor Air Award programs.

Supporting basic, translational, or clinical research projects in rhinology with a focus on female-led investigative teams.

Investigating the interaction between mast cells and fibroblasts in the pathogenesis of EoE.

Supporting food allergy research and clinical trials at the Sean N. Parker Center for Allergy and Asthma Research.

Investigates the role of IgE antibodies in the human immune response to tick bites and how it leads to the development of alpha-gal syndrome, a meat allergy.

Multidisciplinary clinical research focused on the diagnosis and treatment of eosinophilic gastrointestinal diseases.

Serves as the coordinating center for data analysis and clinical trial modeling for the national PrecISE asthma network.

Supports a one-year project focused on the mechanisms, diagnosis, or treatment of mast cell disorders, including mastocytosis and mast cell activation syndrome.

Supporting independent research into type 2 inflammation and its role in diseases like asthma, atopic dermatitis, and nasal polyps.

Participates in the CoFAR network to execute clinical trials on food allergy prevention and immunotherapy safety in pediatric populations.

Promoting crucial innovations in the diagnosis of food allergy.

A randomized clinical trial comparing the effectiveness of three FDA-approved biologics for chronic sinusitis with nasal polyps to determine which treatment works best for specific patients.

Basic research or clinical studies of food protein-induced enterocolitis syndrome (FPIES).

Supports the GF-NOURISH study, which investigates strategies to optimize gluten-free nutrition by reducing ultra-processed food consumption in children.

Defining molecular endotypes of chronic rhinosinusitis to enable precision medicine approaches for treatment.

Assessing the role of fibroblast and dendritic cell interactions in the pathogenesis of atopic dermatitis.

Clinical research and data science applications in emergency care and patient safety.

A five-year project to advance the integration of palliative care into the routine treatment of people with advanced COPD across European healthcare systems.

Investigates common pathways between asthma, COPD, and cystic fibrosis to identify novel therapeutic targets.

Advancing allergy research and understanding of allergic diseases.

A multinational training network for PhD students focused on respiratory precision medicine using systems biology and single-cell transcriptomics for asthma and COPD.

Expanding a program that provides schools with stock albuterol inhalers and spacers to treat respiratory distress in students, focusing on implementation strategies for rural areas.

Implementation of the EXHALE strategy set to improve asthma control and address health disparities through environmental and clinical interventions.

Conducting a randomized trial of 500 patients to compare the effectiveness of three FDA-approved biologics and identify mucus biomarkers to predict patient response.

Aiming to raise awareness of food allergy prevalence and burden among public health professionals and primary care clinicians to improve diagnosis and rescue medication access.

Developing a novel risk analysis tool to reduce respiratory viral infections in schools, specifically to protect children with asthma from flu, RSV, and COVID-19.

Translational immunology project focusing on developing targeted cell-based immunotherapy to treat root cause inflammation in severe asthma.

Investigating the association between dietary fat intake and skin lipidomics in children to determine potential nutritional strategies for eczema prevention.

Investigates new medical treatments for chronic sinusitis with nasal polyps to compare biologic effectiveness and identify mucus-based biomarkers to predict patient response.

Studying the human immune response to tick bites, focusing on IgE monoclonal antibodies and salivary proteins to understand the development of alpha-gal syndrome.

Assessing cross-reactive desensitization and remission with tree-nut sublingual immunotherapy in children.

Tests sublingual immunotherapy (SLIT) protocols for children allergic to multiple tree nuts including cashew and walnut.

Supports state and local health departments in implementing the EXHALE technical package to address environmental and social drivers of asthma disparities.

A multi-center project using multi-omic approaches to identify immune cells involved in FPIES reactions to develop better diagnostic biomarkers.

Investigates the association between dietary fat intake and skin lipidomics in children to explore nutritional pathways for eczema prevention.

A pilot-feasibility study evaluating if an individualized diet based on immune signatures is effective for treating EoE compared to a standard sham diet.

Creates tools to enhance healthy and sustainable food provision and treating food at home, with implications for managing food restrictions and safety.

Using next-generation multi-omic approaches to identify specific immune cells involved in FPIES reactions to improve diagnosis and treatment.